国际眼科纵览

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病理性近视后巩膜葡萄肿的研究进展

黄炜琳 段安丽   

  1. 100730 首都医科大学附属北京同仁医院 北京同仁眼科中心 眼科学与视觉科学北京市重点实验室
  • 收稿日期:2015-09-22 出版日期:2016-02-22 发布日期:2016-03-07
  • 通讯作者: 段安丽,Email:duananli@163.com E-mail:duananli@163.com
  • 基金资助:

    北京市科委首都临床特色应用研究项目(z141107002514173)

Posterior staphyloma in pathological myopia

HUANG Wei-lin, DUAN An-li   

  1. Beijing Tongren Eye Center, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Hospital, Capital Medical University, Beijing 100005, China
  • Received:2015-09-22 Online:2016-02-22 Published:2016-03-07
  • Contact: DUAN An-li, Email: duananli@163.com E-mail:duananli@163.com
  • Supported by:

    Capital Clinical Characteristics Applications Research Program of Beijing Municipal Science and Technology Commission(z141107002514173)

摘要:

我国近视眼患者超过3亿,其中高度近视患者已超过一千万,高度近视中很大一部分为病理性近视(pathological myopia,PM),其并发的眼底病变已成为眼底病中不可逆致盲的首位眼病。在病理性近视眼底一系列退行性病变中,后巩膜葡萄肿(posterior staphyloma, PS)是最基础的病变之一,其发病原因仍无定论,可能是眼轴不断延长、巩膜中胶原的合成及分解紊乱造成胶原蛋白减少共同造成巩膜变薄而不能抵抗眼压的结果。目前病理性近视后巩膜葡萄肿的唯一治疗手段为后巩膜加固术。对于无临床症状或者因PS而产生的并发症需要定期观察,手术时机仍需要大量的临床研究进行评估。

Abstract:

In China, more than 300 million patients suffer from myopia, where in over 10 million patients have high myopia, and a large part of high myopia belong to pathologic myopia (PM). Its correlated ocular fundus retinopathy has become the first reason causing irreversible blindness. Posterior staphyloma (PS) is the most basic disease in the series of pathological degeneration of myopia, and its causes are still unconcluded. The thinning sclera, resulting from the continuous axial lengthening, synthesis and decomposition disorder of collagen in sclera, cannot resist the intraocular pressure, which may be the main cause of PS. At present, the only treatment measure is posterior scleral reinforcement surgery. Regular observation is needed for PS with no clinical symptoms or with complications. The surgery timing still requires a large number of clinical studies to assess.